In the heart of Tokyo's Kabukicho district, a public high school exists unlike any other. Tokyo Metropolitan Mizusho High School, known as Toritsu Mizusho, is a specialized institution dedicated to the mizu shobai, the nightlife entertainment business. The school serves as a last-chance educational environment for its students, offering practical training across several unconventional departments: hostess, host, manager, gay bar entertainer known as geibaa, and soapgirl.

The 2006 live-action television film centers on Yamashita Sanae, a young woman expelled from her previous high school during her senior year. She transfers to Toritsu Mizusho to train as a hostess, navigating a curriculum that includes champagne calls during morning assemblies and fierce nomination competitions during cabaret practice. Sanae is one of many students learning the intricate social skills and etiquette required for success in Kabukicho's entertainment districts. Her classmates include Mari Oda from the fuzoku course, Daichi Nagasawa from the manager course, and Teppei Suga from the gay bar course. The faculty includes Keisuke Tanabe, a sociology teacher who serves as a grounding presence, along with course directors for each department. Headmaster Shigeo Yagura oversees the school while facing scrutiny from officials like Kikuzo Sakuma, the Chairman of the Tokyo Metropolitan School Board, who questions the legitimacy of this educational experiment.

A separate eight-episode television series titled Toritsu Mizusho Reiwa updates the setting to the year 2025. The protagonist is Ishiwata Naoki, a 23-year-old job seeker who accepts a teaching position at the school primarily to obtain the respectable title of sensei for his girlfriend. Only after being hired does he discover the true nature of the institution. Naoki is assigned as the homeroom teacher for Class 3C, a group of students enrolled across four departments: cabaret, host, manager, and service. He struggles to understand a school environment where students practice champagne calls at morning assembly and compete for customer nominations during practical exercises. His students include Manaka Nozomi from the cabaret department, Otake Tetta from the host department, and Imai Shu from the manager department. Naoki quickly becomes entangled in the unexpected troubles his students create, forcing him to confront his own assumptions about education, work, and the nightlife industry.

Both adaptations explore themes of second chances, vocational training, and the social stigma attached to the entertainment industry. The students at Toritsu Mizusho are typically those who have struggled in conventional academic environments, and the school offers them an alternative path to employment and independence. The narrative balances comedic elements with genuine drama, depicting how young people learn professionalism, customer service, and interpersonal skills in a setting that mainstream society often judges harshly. While the subject matter is provocative, the story focuses on the students dedication to their chosen crafts and the teachers who guide them, ultimately presenting the mizu shobai as a legitimate, if unconventional, field of work requiring discipline and emotional intelligence.