Hayate no Gotoku: Can't Take My Eyes Off You is a 12-episode anime series that serves as an alternate retelling of the original Hayate no Gotoku storyline, diverging from the manga's continuity. The narrative centers on Hayate Ayasaki, a hardworking but perpetually unlucky teenager who becomes the butler of Nagi Sanzenin, a wealthy and spoiled young girl. Hayate's life takes a dramatic turn when he is tasked with protecting Nagi and managing her vast estate, all while navigating the chaotic and often absurd situations that arise from their interactions with a colorful cast of characters.

The series introduces a new storyline involving a mysterious artifact known as the "Royal Jewel," which is said to grant immense power to its possessor. Hayate and Nagi become entangled in a quest to locate this artifact, facing off against various adversaries who also seek its power. Along the way, they encounter familiar faces from the original series, including Maria, Nagi's sharp-witted maid, and Hinagiku, a skilled swordswoman and Hayate's close friend. The dynamic between Hayate and Nagi remains central, with Hayate's unwavering loyalty and Nagi's growing dependence on him driving much of the emotional core of the story.

The plot is punctuated by comedic moments, action sequences, and lighthearted romantic undertones, though it also explores themes of responsibility, trust, and personal growth. Hayate's past as a former debt-ridden orphan continues to influence his actions, while Nagi's sheltered upbringing and insecurities are gradually revealed, adding depth to their relationship. The series balances its episodic structure with an overarching narrative, culminating in a climactic confrontation over the Royal Jewel. While the resolution ties up the immediate conflict, it leaves room for further exploration of the characters' relationships and futures.