"SoniAni: Super Sonico The Animation" centers around Sonico, a university student and part-time model who also works as a virtual singer and guitarist for the band "First Astronomical Velocity." The series explores her daily life, balancing her academic responsibilities, modeling career, and musical aspirations. Sonico is portrayed as a kind-hearted and hardworking individual, often juggling multiple tasks while maintaining a cheerful demeanor. Her bandmates, Suzu Fujimi and Fuuri Watanuki, provide support and camaraderie, contributing to the group's dynamic both on and off stage.

The narrative unfolds in a slice-of-life format, highlighting Sonico's interactions with friends, colleagues, and fans. Episodes often depict her navigating challenges such as tight deadlines, creative blocks, and the pressures of fame, all while staying true to her passion for music. The series also delves into her relationships with those around her, including her manager, Kitamura, who oversees her modeling and music careers, and her grandmother, who plays a significant role in her life.

Throughout the series, Sonico's dedication to her craft and her ability to inspire others are recurring themes. The band's performances and recording sessions are integral to the plot, showcasing their growth as musicians and their bond as a group. The anime also incorporates lighthearted moments and comedic elements, often stemming from Sonico's quirky personality and the antics of her friends.

The story maintains a focus on the balance between personal aspirations and professional responsibilities, offering a glimpse into the life of a young artist striving to achieve her dreams. The series does not rely on a heavily serialized plot but instead presents a series of episodic vignettes that collectively paint a picture of Sonico's multifaceted life. This approach allows for a relaxed and engaging exploration of her character and the world she inhabits.