"Argent Soma" is a 25-episode science fiction anime series set in a future where humanity faces existential threats from mysterious alien entities known as "Foreigners." The story centers on Takuto Kaneshiro, a young man whose life is irrevocably altered after a catastrophic incident at the research facility where he works. During an experiment involving a powerful AI system called Soma, Takuto's fiancée, Maki Agata, is killed, and he is left disfigured and emotionally scarred. The incident is covered up, and Takuto assumes a new identity as Ryu Soma, joining the military organization FUNERAL, which is tasked with combating the Foreigners using giant mechs called Golems.

Ryu Soma's motivations are deeply personal, driven by a desire to uncover the truth behind Maki's death and the nature of the Soma project. As he integrates into FUNERAL, he encounters a diverse group of characters, including Hattie, a young girl with a mysterious connection to the Foreigners, and Frank, a stoic and experienced pilot. The series explores themes of identity, loss, and the ethical implications of artificial intelligence and human experimentation. The narrative delves into the origins of the Foreigners, revealing their connection to humanity and the Soma project, which was designed to create a bridge between humans and these alien entities.

As the story progresses, Ryu Soma uncovers layers of conspiracy within FUNERAL and the broader scientific community, leading to revelations about the true purpose of the Soma project and its creator, Dr. Dan Simmonds. The series builds toward a climactic confrontation between humanity and the Foreigners, with Ryu Soma at the center of the conflict. The resolution ties together the personal and philosophical threads of the narrative, addressing the consequences of humanity's attempts to transcend its limitations and the cost of seeking understanding in the face of the unknown. The characters' arcs are interwoven with the larger plot, creating a cohesive exploration of the human condition within a science fiction framework.