"Mahō Shōjo Ore" centers on Saki Uno, a 15-year-old girl who aspires to become an idol to win the affection of her crush, Mohiro. Her life takes an unexpected turn when she discovers that her mother, Yoko, is a retired magical girl. Yoko reveals that Saki must now take up the mantle to protect the world from demons. However, the transformation into a magical girl is far from conventional: Saki turns into a muscular, cross-dressing man wielding a magical bat. This bizarre twist is a result of the magical girl system being tied to the entertainment industry, where popularity and fan support directly influence the strength of the magical girls.

Saki is joined by her best friend, Sakuyo Mikage, who also becomes a magical girl and undergoes a similar transformation into a muscular man. Together, they form a magical girl duo under the guidance of their manager, a talking mascot named Kyubey. The series explores their battles against demons, which are often tied to the entertainment world, as well as their struggles to balance their magical duties with their personal lives. Saki’s crush on Mohiro becomes complicated when she discovers that he is actually a demon hunter named Ryōsuke, who harbors feelings for her male magical girl persona.

The narrative blends action, comedy, and absurdity, often parodying traditional magical girl tropes. The characters’ transformations and battles are exaggerated and humorous, contrasting with the more serious undertones of their personal struggles and the darker aspects of the entertainment industry. The series also delves into themes of identity, self-acceptance, and the pressures of fame, as Saki and Sakuyo navigate their dual lives and the expectations placed upon them. The dynamic between the characters, particularly Saki’s interactions with Ryōsuke and Sakuyo, adds emotional depth to the otherwise comedic and surreal storyline.