"Ace wo Nerae!" centers on Hiromi Oka, a high school student who joins the tennis club at her school, Nishi High. Initially, Hiromi struggles with self-doubt and lacks confidence in her abilities, but her life takes a turn when she encounters Reika Ryūzaki, a stern and highly skilled tennis coach. Reika recognizes Hiromi’s potential and pushes her to develop her skills, often through rigorous and demanding training methods. Hiromi’s journey is marked by her determination to overcome her insecurities and rise to the challenges presented by both her coach and her rivals.

The narrative explores Hiromi’s growth as a tennis player and as an individual, highlighting her relationships with those around her. Her rivalry with Kyoko Otowa, a talented and confident player, serves as a key dynamic, driving Hiromi to improve and compete at higher levels. The series also delves into the pressures of competitive sports, the importance of perseverance, and the emotional toll of striving for excellence.

Supporting characters, such as Hiromi’s teammates and friends, add depth to the story, providing both encouragement and conflict. The series balances intense tennis matches with personal drama, showcasing the challenges of balancing ambition, relationships, and self-discovery. Through its focus on Hiromi’s journey, "Ace wo Nerae!" presents a compelling portrayal of athletic ambition and personal growth within the competitive world of high school tennis.