Guelph Ganz is a secondary antagonist in the anime Star Blazers 2199, serving as the executive officer under Colonel Shultz at the Gamilas forward operating base on Pluto. He is a male adult with brown hair and brown eyes, and he is typically seen in his Gamilas military uniform. His character marks a significant departure from earlier adaptations; in Star Blazers 2199, Ganz is portrayed as a capable and fair officer who acts as the level-headed eyes and ears for his commanding officer, Shultz. Unlike the bumbling subordinate of previous versions, this iteration of Ganz is defined by his competence and his pragmatic sense of duty within the rigid structure of the Gamilas Empire.

His personality is characterized by a calm professionalism and a sense of fairness that extends to his own crew. He is not driven by fanatical zeal or personal glory but rather by a desire to fulfill his duties while minimizing unnecessary losses. This motivation becomes clear when the Earth battleship Yamato begins its assault on the Pluto base. Ganz assists in calculating firing angles for the base's powerful Reflection Satellite Cannon in an attempt to destroy the enemy ship, but when the weapon fails and the base faces certain destruction, it is Ganz who persuades Shultz to order an evacuation to prevent further unnecessary casualties among their own forces. This act highlights his primary motivation: the survival and well-being of his subordinates, even in the face of failure and disgrace. He understands that returning to the Gamilas homeworld in shame would be a severe punishment, yet he prioritizes saving lives over a futile last stand.

In terms of role within the story, Ganz functions as the pragmatic advisor to Shultz, frequently offering sound tactical assessments and counsel. He is one of the first Gamilas officers to directly engage the Yamato and report on its unprecedented capabilities, noting its ability to perform space jumps from Mars to Jupiter and beyond. His key relationships are central to his character, most notably his unwavering loyalty to Colonel Shultz. The two share a professional bond forged by their shared circumstances, as both belong to a Gamilas underclass with differently colored skin, considered inferior by pure-blooded Gamilas like Commander Goer. This shared status as second-class citizens in their own empire adds a layer of tragic complexity to their service, as they are forced to prove their loyalty to a regime that looks down upon them. Ganz also shows respect and sorrow for his comrades, demonstrated when Lieutenant Commander Jarletora sacrifices his ship to buy time for Shultz and Ganz to escape the Yamato's pursuit.

Throughout his limited screen time, Ganz demonstrates notable development from a supporting tactical officer to a key figure in the Pluto base arc's dramatic conclusion. His abilities are not combat-oriented but lie in strategic analysis, quick calculation, and sound military logistics. He is the one who calculates the trajectory for the satellite cannon and later conceives the necessity of the base's evacuation. His most significant act is grounding his superior officer in reality, showing his ability to influence command decisions through reason rather than force. The character meets his end alongside Shultz after they are given the Desler Torpedo by Leader Desler to destroy the Yamato. When the special warhead fails and the sun's flare destroys their ship, Ganz dies with his commander. In a final acknowledgment of his service and sacrifice, Ganz is given a two-rank posthumous promotion, and his family is granted honorary Gamilas citizen status, a rare honor for those of his racial background. His death serves as a poignant end for an antagonist who, while opposing the protagonists, was motivated by a sense of loyalty and duty rather than pure malice.