Movie
Description
Izana Shinatose is a resident of the generation ship Sidonia and a pilot of the giant humanoid weapons known as Gardes. Izana belongs to a genetically engineered third gender, a biological classification separate from male or female that emerged among humans over centuries of space travel. This biology allows for transformation into a male or female body based on romantic attraction to a partner, and it also permits asexual reproduction through parthenogenesis.

In terms of background, Izana is a clone of Yure Shinatose, a scientist who is a member of Sidonia's ruling immortal council and Izana's grandmother. Izana lives with this grandmother and maintains regular communication with her. Initially serving as a Garde pilot trainee with the designation TS-291, Izana is later promoted to Unit 723.

Izana is the first person on Sidonia's surface to befriend the protagonist, Nagate Tanikaze, treating him with kindness when he struggles to adapt to his new life. The personality is reserved and empathetic, but also capable of displaying jealousy, particularly toward other women who show interest in Nagate, such as Shizuka Hoshijiro and the hybrid being Tsumugi Shiraui. Despite this romantic rivalry, Izana maintains a strong friendship with fellow pilot Yuhata Midorikawa, at one point protecting her in combat at significant personal risk.

As Izana spends more time with Nagate and develops romantic feelings for him, the body begins an involuntary biological transition into a female form. This transformation manifests in physical changes including breast development, and becomes unmistakable when the standard pilot suit no longer fits the altered physique. The gender of a neutral person such as Izana is determined by the sex of the partner to whom they are attracted.

During combat against the Gauna, specifically in an encounter with a Gauna imitating Shizuka Hoshijiro, Izana suffers critical injuries that result in the loss of the right arm and left leg. These lost limbs are replaced with advanced prosthetic replacements. The prosthetic arm features a ten-finger design that enhances dexterity for piloting, with the ability to perform fine tasks such as tying bow knots or peeling fruit. A neural interface system is integrated into the Garde unit, channeling sensor and radar information directly into the brain through the prosthetic arm. This modification provides superior long-range detection capabilities that exceed even Sidonia's own systems, making Izana exceptionally well-suited for reconnaissance and spotting duties in battle.

Izana forms a significant friendship with Tsumugi Shiraui, the human-Gauna hybrid, assisting her in moving covertly through Sidonia despite regulations against such actions. Following Sidonia's successful colonization of the Lem star system and the defeat of the Large Mass Union Ship, approximately ten years later Izana is among the crew members who depart aboard a repaired Sidonia to seek new planetary colonies elsewhere in space.