Simon Raider spearheads the medical division within Oblivion Bay, a fortified shelter safeguarding humanity's remnants after the Dractor alien invasion pushed the species to the brink of extinction. Following the catastrophic "Day of Destruction," where Reiji Amemiya lost his family, Raider assumed the role of Reiji's foster guardian.

Raider orchestrated Reiji's transfer to the Shelter Ixia research facility, overseeing the study and development of the young man's latent "Psycho-Rise" psychic abilities throughout his three-year residency there, aiming to understand and enhance these powers under controlled conditions before Reiji's eventual integration into Ixia's general population.

Beyond his guardianship of Reiji, Raider's responsibilities encompass medical oversight of the shelter system and likely extend to the operation of memory manipulation technology employed to maintain a perceived peaceful existence for the survivors.