Misuzu Kadenokouji is a first-year student at Kyoto Municipal Horikawa Senior High School, placed in Class C while Naomi Katagaki and Ruri Ichigyou belong to a different class. Despite this separation, she serves with them on the Student Library Committee. Her friendly, bright, and cheerful personality makes her stand out positively without causing annoyance, contributing to her popularity and status as a class idol. Her cute appearance and demeanor often lead male classmates to develop feelings for her; Naomi Katagaki explicitly states she aligns with his preference for "cute-type" girls, though he feels no romantic attraction towards her.

Physically petite with a small face, pale white skin, and a slim build, she possesses notable brown eyes and jaw-length reddish-brown hair featuring light auburn tones and curly tips.

Within the Library Committee, Misuzu shows initiative by participating in the annual secondhand book fair and later organizing members to collect additional donations after a disappointing initial haul. She expresses regret and gratitude when Ruri Ichigyou contributes her late grandfather’s book collection. Misuzu is observant, discreetly watching the developing relationship between Ruri and Naomi from a distance and actively supporting their romantic progression. She reacts with visible excitement upon witnessing moments of closeness between them, such as an embrace in the library.

Initially facing Ruri's reserved and distant attitude towards social interactions, including her own friendship attempts, Misuzu persists. She uses affectionate nicknames like "Ruri-rin" or "Ruurii" for Ruri. Her consistent warmth eventually leads to a significant shift, evolving their relationship into a genuine friendship demonstrated through shared activities like shopping trips.

She also features in the spin-off light novel "Hello World if: Kadenokouji Mirei wa Sekai de Saishou no Shitsuren wo Suru," which centers on her character.