Shuuichi Natori sees Ayakashi—supernatural entities invisible to ordinary humans—and works as an exorcist who tracks and subdues spirits. He commands three Ayakashi to assist him and employs specialized paper dolls for surveillance or tracking targets, reflecting a methodical approach to his duties.

A constantly shifting black salamander-shaped birthmark travels across his body, serving as a distinctive identifier. His demeanor appears generally approachable and sociable, though he adheres strictly to personal principles and boundaries.

Alongside exorcism, he maintains a separate career as a renowned actor, balancing public visibility with the secrecy of his supernatural work. He operates primarily in Japan, navigating both human and spiritual realms.

His interactions with others, including Takashi Natsume, involve shared experiences with Ayakashi and exorcism, occasionally leading to collaborative efforts against supernatural threats. Background details like his origin, age, or chronological development across the broader series and films remain undocumented. In "Natsume Yujin-cho the Movie: Ephemeral Bond," he appears in a supporting capacity, contributing to the central narrative involving the protagonist and Nyanko-sensei’s predicament without elaboration on his precise role.