Kyōsuke Isazu leads Kiryu Hospital while conducting cutting-edge research at the Kiryu Biotech Research Facility, pioneering advancements in artificial life through his revolutionary "Carbon Nanostructure" technology. His work on synthetic organisms intersects with a deeply personal mission: reviving his comatose daughter Yuzuha, whose condition after a tragic accident fuels his descent into morally ambiguous experimentation.  
Amid the chaos of the "Burst" incident, Isazu uncovers cloned replicas of Yuzuha within the sealed research facility. These hollow shells, devoid of consciousness, become the focus of his reckless attempts to restore her mind, using a neural interface to manipulate the clones remotely. As desperation mounts, he exploits allies and coerces protagonist Aiko Tachibana into hazardous trials involving the unstable Malignant Matter, dismissing collateral damage in his single-minded pursuit.  
His obsession culminates in a catastrophic fusion of his consciousness with the clones, overloading his psyche when confronted by the irreconcilable gap between his idealized salvation and the grim reality of his ethical transgressions. The mental fracture leaves him comatose, paralleling Yuzuha’s state—a poetic collapse of creator and creation.  
Decades-old ties to colleagues Susumu Kurose and Akiko Nanbara, forged during their academic years, erode as Isazu prioritizes his daughter over collaboration, severing moral and emotional bonds. His story closes with an indefinite coma, an open-ended testament to the perils of ambition untethered from ethics. The arc weaves parental devotion with the hazards of scientific overreach, framing life’s fragility against the cold calculus of progress.