Orochimaru belongs to the Fire Clan and descends from the Snake Clan. Trained by Hebi Sennin, he is Kabuki's brother and serves as a ninja under Mr. Shogun, an affiliation that sets him apart. His personality blends nihilism with a talent for female disguises, a skill he leverages for tactical evasion, such as posing as a kabuki actor to escape Daimonist attacks. Tsunade pursues a romantic interest in him, usually resulting in his embarrassment or indifference.

Within the Oboro-hen OVA, Orochimaru operates as both a kabuki actor and mystic. He joins forces with Ziria, Kumokiri, and Tsunade to thwart the wizard Jashinsai's plot to revive a clockwork soldier using the sealed beast Hiruko's power. Demonstrating reliability and wisdom within this alliance, he utilizes mystical arts, including summoning a snake composed of blue fire to aid the group during critical confrontations. His role proves integral to the team's efforts in protecting Princess Yuki and preventing Jashinsai's domination of Jipang.

Across other franchise media, Orochimaru appears in multiple installments. He maintains a strained relationship with Ziria in *Tengai Makyō: Fuun Kabukiden*, playing a significant role by sending destination letters to Kabuki. He also features as a playable character in *Tengai Makyō Shinden (Kabuki Klash)* and makes cameo appearances in titles such as *SameGame + Tengai Makyō Jikei*. While the Oboro-hen adaptation streamlines elements from the original game, like removing Ziria's summonable toad companion, it retains Orochimaru's core traits and mystical capabilities.