Nadeshiko Kiriya is the eldest daughter of the aristocratic Kiriya vampire clan, led by her mother Sumi. She possesses long green hair, blue eyes, an adult appearance, and a prominent bust. Her family tradition involves selecting human partners to sustain their lineage and provide blood donors, a process causing donor degeneration over time. Nadeshiko's duty includes evaluating the protagonist Daisuke's suitability as a partner within these secretive practices.

Her past holds deep trauma. Manipulated by her mother's schemes to designate a successor, she was coerced into an affair with a man from a wealthy family, resulting in the degeneration and loss of her true love, who served as an unofficial donor. Nadeshiko also harbors profound guilt over the death of her frail youngest sister, Fujino, caused by an act of jealousy that accidentally exploited Fujino's health. These events fuel her internal conflict between embracing her mother's manipulative legacy or rejecting it.

Her story arc centers on this conflict. Influenced by Daisuke in her specific route, she chooses defiance against her mother's control, culminating in arson that destroys the Kiriya estate. Her relationship with Daisuke involves physical intimacy, with distinct biological reactions during arousal noted as a trait. While appearing in other media like an OVA adaptation, her core narrative progression remains consistent with the source material's portrayal of her rejection of the family's vampiric traditions.