Don Giuliano holds the title of Italian Jr. Boxing Champion and represents Italy in the World Jr. Tournament. He cultivates a mafia-inspired persona, leading a group embracing the "Sicilian Dandy" mentality and known as the "Jr. Mafia." His characterization prioritizes style, sophistication, and an image of "coolness," frequently appearing in regal outfits and maintaining an elegant demeanor.

He employs strategic and underhanded methods against rivals, notably orchestrating interference to sabotage Team Golden Japan Jr. before their World Tournament match. However, he strictly adheres to formal boxing rules during actual competition.

Family legacy is central to his background. He possesses a young son, whose existence surprises figures like Black Shaft. Giuliano explicitly intends for this son to inherit his position and perpetuate the family's influence within boxing and his established circles.

In the sequel "Ring ni Kakero 2," featuring the next generation, Giuliano suffers from deteriorated physical condition, including hand problems. His story concludes when he is murdered during the Italy Chapter. This assassination ignites a power struggle within his organization among his sons, Caesar and Nero, over leadership succession. His death and its aftermath directly impact the plot involving Rindo Kenzaki and other new characters.

Beyond boxing, he maintains connections with other international champions, including Black Shaft. During the Pacific War arc (Japan vs. USA), Shaft brings Giuliano and associates like Dinobaze to Japan to observe the matches, highlighting alliances among global boxing rivals.