Ryo Ishizaki commences his football career as captain of Nankatsu elementary school's team. Initially prone to errors and clumsiness, his exceptional determination becomes his defining trait. Through relentless effort and sheer guts, he evolves into a dependable defender, recognized as a moral pillar for Nankatsu and Japan's junior teams, often wearing jersey numbers 14 or 4. His pivotal friendship with Tsubasa Ozora critically influences Tsubasa's choice to stay at Nankatsu over transferring to Toho Academy. Progressing to Nankatsu High School, Ishizaki's development continues, culminating in his appointment as team captain. His growing tactical understanding and strong work ethic draw comparisons to Hikaru Matsuyama, highlighting his advancement in teamwork and strategy despite lacking signature dribbling or shooting prowess. During the Madrid Olympics, his technical skills demonstrate significant improvement, enabling him to outmaneuver opponents and deliver key assists. In *Captain Tsubasa IV: Pro no Rival-tachi*, Ishizaki leads Nanbu University to consecutive University Championships. Post-university, he follows Tsubasa to Sao Paulo, Brazil. Non-canonical game routes also place him within the Brazilian league alongside players such as Santana. Later, in *Captain Tsubasa V: Hasha no Shogo Campione*, he returns to Japan, joining professional club Nankatsu SC and partnering with French forward Louis Napoleon. His known techniques include the stamina-sacrificing "Face Block" for intercepting powerful shots and the "Wild Monkey Buster" shot, though his practical shooting ability remains constrained by base stats. Within the *Next Dream* arc, Ishizaki advances to the international stage as a defender for Italian club Lombardia. His playing style centers on tenacious physical defense, prominently featuring the "Face Block" technique to disrupt opposition attacks. This phase marks his transition from domestic competition to participation in elite global tournaments.