Fujiko F. Fujio appears as a character within the narrative of "2112: The Birth of Doraemon." The film opens in November 1969, showing him as a manga artist laboring under deadline pressure to create a new project. He grapples with creative block while his team works around him, staying late after others depart. Returning home, he voices frustration over his lack of time and wishes aloud for a time machine to access his future creations.

This scene forms a framing device that transitions directly into Doraemon's origin story. His appearance links to the franchise's creative genesis, positioning him as both the real-world creator and an integral narrative element. His conceptualization of Doraemon occurs here, where his wish for technological assistance manifests through the subsequent tale of the robotic cat's 22nd-century creation.

Biographical elements mirror Hiroshi Fujimoto's actual career. The character is shown creating manga during the late 1960s period coinciding with Doraemon's original serialization. His decades-long collaborative partnership with Motoo Abiko is referenced through their childhood friendship and professional bond starting in elementary school. His professional background includes mentorship under Osamu Tezuka after moving to Tokyo in 1954, and co-founding the Shin Manga-To group with fellow artists Fujio Akatsuka and Shotaro Ishinomori.

The film concludes by returning to Fujiko F. Fujio at his desk, completing the narrative frame initiated by his creative struggle. This circular structure underscores his role as the originator of the Doraemon concept within the film's fictional context.