Imprisoned in Yanome when she first appears, Pioran aids Parona and March's escape by staging a medical crisis to distract guards. Though references to poisoning soldiers hint at a troubled past, her exact reasons for imprisonment are unclear. Following the prison break, she journeys with Parona and March, witnessing March's clash with the Spirit Bear before fleeing Yanome by wagon under soldier attacks. Years later in the forest, Pioran encounters Fushi, an immortal being, initially mistaking him for March. Recognizing Fushi's true nature, she persistently follows him. Despite his indifference, she leverages his immortality for survival, convincing him to provide food. During their travels, she teaches Fushi human language, writing, and practical skills like cooking, shaping his understanding of humanity. She guides him to Takunaha, her homeland, where they settle with her lover, Booze Man, and his adopted son Gugu. There, she documents the threats known as Nokkers and supports Fushi during attacks, preventing Rean's parents from endangering themselves. After Gugu's death, Fushi attempts to leave Takunaha to protect Pioran and Booze Man from Nokkers. She disregards his wishes and rejoins him. She suggests relocating to the isolated Sarlnine Forest but is tricked onto a boat to Jananda Island, resulting in her imprisonment. Fushi locates her and promises rescue, which she initially resists, urging him to prioritize others. During Jananda's final battle, she expresses pride in his growth before Hayase tranquilizes her. Post-rescue, Fushi reunites with Pioran in Zedan. They journey to Sarlnine Forest, where he prioritizes her safety during Nokker attacks. Aging brings decline in her physical and mental health, manifesting as weakness, memory loss, anger, and paranoia about Yanome. When Fushi asks her final wish, she expresses a desire for youth but states she has lived fully. Preparing for death, she summons the Beholder and requests reincarnation as something useful to Fushi. Her soul transforms using Fushi's flesh, implied to become a white horse. Pioran is characterized by resilience, pragmatism, and a lust for life, often prioritizing survival through resourceful or unconventional means. Her backstory includes references to con artistry and itinerant merchant work, though details are sparse. She exhibits a complex moral code, balancing self-interest with protective instincts, particularly toward Fushi and children. Her relationship with Fushi evolves from practical reliance to deep mutual care, positioning her as a foundational influence on his humanity.