As primary antagonist of the Papillon Rose franchise, Regina Apis founded and leads the organization Dinasty. Her goal is global conquest through control of sexual energy, launching this campaign from Tokyo's Shinjuku Kabukichō pleasure district.

She cuts a regal and imposing figure. Manga art depicts her with silver hair styled like Rita Repulsa, featuring cloth pieces hanging from the ends, and a long gown adorned with transparent bee-like wings. The anime OVA portrays her with blue skin, pointed ears, gray hair wound into points on each side of her head (with long falls reaching the floor), brown eyes, and four translucent insect-like wings. Her attire here is a full-length, dark violet gown with a fur collar.

Her significant backstory reveals she placed Queen Flora into deep frozen sleep and seized the Holy Flower Orb, motivated by jealousy. Unable to activate the orb herself, she lured the Papillon Senshi to her lair. She commands minion generals known as the Sisters (Sister Biene, Sister Pchela, Sister Melitta, and Sister Abeille) and is master to the three heavenly queens and the group Meine Liebe (Kreuz, Karo, Hertz, and Piku), four men tasked specifically with bringing her to climax.

Regina Apis mastered all sexual techniques worldwide but inherently cannot achieve her own climax, a core trait driving her motivations. Her demeanor is consistently bad-tempered and she openly relishes her mission of domination.

Her ultimate fate after the manga's final chapter remains unknown. Across adaptations (manga, ONA, OVA, Rebuild series), she consistently leads the antagonistic forces opposing the Papillon Senshi. Specific plot details from later series like "Papillon Rose R", "Papillon Rose G", or "New Season" are not detailed in the available sources.