Sayuki Tezuka is a 20-year-old nurse with a slim physique, standing 154 centimeters tall and weighing 48 kilograms. Her pale skin is complemented by long, blond ringlets styled into twin braids and a side part. Her hazel eyes are shaped in a tareme style. She possesses notably large breasts, with a bust-waist-hips ratio of 92-58-90 centimeters, which feature nipple piercings.

Her attire consists of a nurse uniform, a nurse's cap, a dress, a skirt, evening gloves, sandals, and bandages. She also wears glasses. In her professional role as a nurse, her personality is marked by clumsiness. She engages in bondage and is subject to psychological trauma.