Dr. Mashirito is an evil scientist and the primary rival of Senbei Norimaki, serving as a main antagonist in the Dr. Slump series. His intelligence equals or surpasses Senbei's, and his personality exhibits significant perversion. His initial ambition involves world domination using robotic suits named Caramel Man, beginning with Caramel Man 001. After a magic mirror reveals Arale Norimaki as the world's strongest robot, he targets her for defeat. An early confrontation in Penguin Village fails when Gatchan consumes Caramel Man 001.
He evolves into a full cyborg, adopting the identities Caramel Man 008 and later Caramel Man 009. During the "Who's the Strongest in the World?" tournament, he reaches the finals against Arale. Though he incapacitates her with a specialized ray gun, Obotchaman impersonating Arale defeats him, reducing him to a single bolt. Physically destroyed yet persistent, he returns as a ghost, vowing world conquest and witnessing Senbei's rocket launch. His legacy continues through his son, Dr. Mashirito Jr., who creates the evil Arale counterpart Abale-chan in a spin-off one-shot.
In film appearances, he joins other characters at a haunted summer resort in "Dr. Slump and Arale-chan: N-cha!! Wakuwaku Hot no Natsuyasumi" (1994), encountering vampire antagonist Vandora in a minor role. He also attends a banquet in "Dr. Slump and Arale-chan: N-cha! From Penguin Village With Love" to prove superiority over Senbei.
Cross-series appearances include Dragon Ball Super, where he escapes HFIL (Home For Infinite Losers) to sabotage Senbei's award ceremony. He administers "Playtime X" to Arale, inducing a rampage requiring intervention from Goku and Vegeta. As a ghost, Beerus erases him from existence using the Hakai technique, marking his permanent demise. In video games, he serves as an antagonist in Famicom Jump: Hero Retsuden and the main villain in Jump Super Stars and Jump Ultimate Stars, orchestrating plans to dominate the Jump universe.
Conceptually, author Akira Toriyama modeled him after his first editor, Kazuhiko Torishima, using syllable reversal of the editor's name for the character's designation. This design followed criticism that initial villain concepts lacked sufficient menace.