Michiko Azuma is the older sister and steadfast guardian of protagonist Jō Azuma, who exhibits significant attachment to her. Her background and daily life remain largely unexplored beyond this core familial role.

During the narrative, Michiko confronts the broader cataclysmic events threatening Earth, facing the cosmic threat of Genma alongside others. Her emotional response to these events is captured in a specific scene where her expression conveys profound emotional weight, reflecting both strength and vulnerability in the face of impending destruction. This moment underscores her human reaction to overwhelming existential danger.