Doctor Dee serves as Endor College faculty, specializing in magical transformation experiments and closely collaborating with Headmistress Madam Mumblechook. His research relentlessly pursues using the rare "fly-by-night" flower to grant humans permanent magical abilities, driven by a conviction that unlimited power would revolutionize the world. He approaches magic scientifically, equating electricity to magical energy and chemistry to potion-making, while asserting innocence enhances magical absorption.

Years before the main events, a catastrophic laboratory explosion involving unstable fly-by-night experiments destroyed Endor's original research facility and cost Doctor Dee his right arm. This incident directly caused his current physical condition: a mechanical prosthetic arm with extendable capabilities and clamp-like hand functions, alongside other cybernetic enhancements. These early failures also mutated volunteer students into unstable magical entities.

Throughout the narrative, Doctor Dee conducts unethical experiments on animals and humans. He transforms animals, including a grey cat named Gib, into hybrid creatures imprisoned in Endor's lab. His methods escalate to kidnapping a human child, Peter, intending to achieve magical "rebirth." These experiments temporarily alter Peter into a winged humanoid before destabilizing him into a gelatinous, magic-absorbing monster.

Doctor Dee's partnership with Madam Mumblechook positions him as her primary enforcer, executing their shared vision despite recurring failures and inherent research dangers. Their collaboration culminates in a second laboratory disaster during Peter's transformation, where counter-spells undo all their work. His character remains unrepentant; his relentless pursuit of power through unethical means defines his role as a secondary antagonist.