Dr. Tenma hosts a New Year's party at his mansion, attended by Osamu Tezuka and numerous characters from Tezuka's works. Amidst the festivities, Tezuka abruptly vanishes. Dr. Tenma joins the immediate search to locate him before additional guests arrive, collaborating with other attendees like Dr. Ochanomizu, Hamegg, and Higeoyaji. This collective effort unites Tezuka's characters in resolving the mystery of his disappearance within the mansion.