Shiori Misaka is a 16-year-old girl with light skin, blue eyes, and dark brown hair reaching her neck, measuring 157 cm tall and weighing 43 kg. Her physical frailty results from a life-threatening illness present since birth, causing frequent school absences. Despite this, she often visits her school grounds, even in snowy weather, to eat ice cream and meet someone important, demonstrating her determination to experience normalcy against medical advice. Her persistent presence outside school reflects a key personality aspect: a desire to connect with others while downplaying her condition as a "common cold" to avoid worry.
Her family background includes a strained relationship with her older sister, Kaori Misaka, who distanced herself after learning the severity of Shiori's prognosis. This rejection caused Shiori significant emotional pain, fueling her longing to reconnect and recreate their past closeness. This burden contributed to suicidal tendencies, including self-harm with a box cutter, actions that ceased after encountering Yuichi Aizawa and Ayu Tsukimiya, whose friendship provided happiness and diminished her self-destructive impulses.
Shiori's development centers on her growing acceptance of life and reconciliation with Kaori. As her next birthday approached—a point doctors indicated she might not survive—she received permission to attend school normally for one week. Yuichi organized a birthday party at a local café; Kaori initially avoided the event but later appeared, leading to their reconciliation. This acceptance fulfilled Shiori's deepest wish and markedly improved her emotional state. Later, during a visit to a park fountain with Yuichi, she revealed her earlier suicide attempt on the day they met, crediting him and Ayu with renewing her will to live. Shortly after, her health deteriorated requiring hospitalization, but she later experienced an unexpected and complete recovery. She expressed tearful relief at surviving, acknowledging her previous façade of strength.
Within the crossover context, Shiori appears among characters from multiple series attending Kaginado Academy. Her portrayal retains core traits: she references counting down to her birthday while emphasizing her reconciliation with Kaori. Her fondness for ice cream remains consistent, depicted as an ongoing habit regardless of weather. This representation integrates her into the ensemble without altering her fundamental character arc or relationships.