Nanami Hisami, called Nanamin, is the 13-year-old youngest member of the idol group Wake Up, Girls!, joining via audition in late 2013. Her designated image color is purple, and her symbolic animal in the main series is the wolf. Nanami displays a confident, prideful personality while remaining approachable. She diligently practices singing, acting, and piano, driven by her aspiration to become a top idol and achieve her dream of performing at the Hikarizuka Theater. Her commitment to Wake Up, Girls! solidified after an overnight trip to Kesennuma, where learning about fellow member Mayu Shimada's past inspired her full devotion.

In the spin-off "Wake Up, Girl Zoo!", Nanami is portrayed as a fox character, distinct from her main series wolf association. Within this zoo setting, she actively participates in revitalization efforts like fundraising at an aquarium, distributing leaflets, and proposing animation improvements to attract visitors, with her ideas evaluated by others. She also features in specific ending sequences for this spin-off, including one where her body appears rigid and statue-like during the dance.

Later media, including the "New Chapter" storyline, showcases Nanami's adaptability and dedication. During a bathhouse performance where Minami Katayama is delayed, Nanami disguises herself in Minami's tiger costume to maintain the act; though a mistake reveals her identity, the audience reacts positively. She further contributes by collaborating on original songwriting that reflects the group's experiences and identity. In the theatrical release "Beyond the Bottom," Nanami and the group incorporate elements from their animal-themed spin-off by performing with animal masks during their national tour. She consistently maintains a supportive role within the group dynamic across all appearances.