Dr. Natsuki Enra works as a nurse in Y Academy's infirmary while also acting as second-in-command to Kinya Daiouji in the Yo-kai Special Power (YSP) organization. She is the reincarnation of Smogmella.

She possesses a slender figure, dark blue eyes highlighted by aquamarine eyeshadow and eyelashes, and pink lipstick. Her long, light cyan hair typically obscures her right eye. She wears yellow earrings and sports cyan nail polish. Her outfit consists of a loose white lab coat over a dark-blue, sleeveless turtleneck sweater open at the shoulders, a yellow pencil skirt, and teal high heels.

Her personality blends an alluring presence with sincere dedication to student well-being and YSP objectives. She expertly captivates individuals like Ryusuke Kyubi while remaining professional. She holds deep knowledge of spiritual beings, including Yo-kai and Onryo. Outside work, she practices yoga and similar exercises to maintain her physique.

She first appears after Jinpei Jiba befriends Wampus, commending his YSP abilities and providing him with the YSP Watch to unlock his potential. Later, she observes Jinpei and Sandayu battling O Eater, analyzing their combat skills. She subsequently reports to Kinya Daiouji on their Yokai control and abilities, recommending their transfer to Y Academy.

Her favorite food is floral-infused Café au Lait.