Senku Ishigami, a scientifically gifted individual, emerged as humanity's central figure in rebuilding civilization after a global petrification event. Adopted by Byakuya Ishigami, his birth origins remain unclear. From early childhood, he displayed intense fascination with science—particularly astronomy and space—conducting experiments like building a functional miniature rocket and designing a specialized swimsuit to aid Byakuya's astronaut training. He corresponded with scientist Dr. Xeno for experimental guidance and traveled internationally, including to Africa for Ebola research. On June 3, 2019, petrification turned all humans to stone. Senku retained consciousness for roughly 3,700 years, meticulously counting 117,354,893,870 seconds before reviving on April 1, 5738. He theorized petrification causes—alien invasion, human error, or a virus—and deduced nitric acid combined with ethanol could reverse it, creating "revival fluid." This allowed him to depetrify childhood friend Taiju Oki, who helped revive Yuzuriha Ogawa. Reviving Tsukasa Shishio to counter a lion attack proved pivotal. Tsukasa opposed rebuilding modern civilization, fearing renewed corruption. Their ideological clash escalated when Tsukasa destroyed adult statues and captured Yuzuriha. Senku surrendered the revival formula to save her but refused to abandon science. Tsukasa fatally wounded Senku, though partial neck petrification prevented death. After recovery, Senku sent Taiju and Yuzuriha as spies into Tsukasa's group while founding the "Kingdom of Science" to counter Tsukasa's vision. Traveling later, Senku rescued Kohaku using pulley mechanics. She led him to Ishigami Village, founded by descendants of Byakuya's astronaut crew. Initially distrusted, Senku won villagers over by demonstrating scientific principles—dubbed "sorcery"—defeating self-taught scientist Chrome in a contest before mentoring him. To cure priestess Ruri's illness, Senku spearheaded antibiotic production using sulfur. He engineered innovations like magnet-based iron extraction and crafted ramen to incentivize cooperation, forming alliances with craftsman Kaseki and mentalist Gen Asagiri, who defected from Tsukasa after witnessing Senku's science. Senku expanded the Kingdom of Science by reviving specialists like sailor Ryusui Nanami for sea voyages to uncover petrification's origins. He demonstrated expertise in chemistry, physics, and engineering, recalling vast scientific knowledge accurately. Multilingual in English and others, he employed Morse code covertly. As a strategist, he delegated tasks by allies' strengths—Taiju for labor, Kohaku as warrior, Gen for diplomacy—while acknowledging his own physical and craftsmanship limitations. Logically driven and confident, Senku prioritized efficiency but showed fierce loyalty, risking his life for allies. He championed science for collective human advancement, opposing Tsukasa's ideals. Romance he dismissed as illogical yet supported among friends. Vulnerability surfaced around his adoptive father; discovering Byakuya's final resting place triggered rare distress. Physically, he has white-to-green spiked hair, red eyes, and petrification scars healed after later rocket depetrification. Later missions involved global exploration to identify the petrification source. In South America, he received a friendship cloak from Suika. Confronting new factions, he advanced technology, unwavering in his mission to revive humanity and solve scientific mysteries.