Kikuko serves as a member of the Kanto region's Elite Four, specializing in Ghost-type Pokémon. Depicted as an elderly woman requiring a cane for mobility, her appearance varies across different iterations. Early game depictions show her in a long violet sleeveless dress over a white shirt with black shoes, while later designs feature a shorter purple dress with sleeves, gray leggings, and purple shoes. Her cane sometimes incorporates Gengar-like design elements and may embed a Poké Ball capable of housing the Pokémon. Her background establishes a longstanding youth rivalry with Professor Oak. Their relationship deteriorated over philosophical differences regarding human-Pokémon bonds; she openly rejected Oak's view of Pokémon as equals, labeling the idea "crazy." This disagreement contributed to her becoming, in Oak's words, a "twisted old woman" who harbored animosity toward children and lacked meaningful friendships. Within the narrative of Pokémon Generations, she appears alongside fellow Elite Four members awaiting a challenger. Facing the challenger after Bruno's defeat, she initiates battle using an Arbok. After its loss, she questions if the challenger collects Pokémon merely for Oak's Pokédex, dismissively referring to Oak as an "old coot," then deploys Gengar against the challenger's Rhydon. Her battle demeanor exhibits theatrical flair, including dramatic Pokémon releases and expressive reactions, aligning with her "Large Ham" personality. Her team composition consistently emphasizes Ghost and Poison dual-types. Initial game appearances feature Gengar, Golbat, Haunter, and Arbok. Later iterations adjust this lineup but maintain Gengar as her signature Pokémon. The name "Kikuko" derives from Japanese elements: "鬼" (ki, meaning ghost or demon) and "菊" (kiku, meaning chrysanthemum). Alternative interpretations of her English name, Agatha, connect it to words like "aghast," "hag," or "agony," with potential allusion to author Agatha Christie.