Eliza is the mate of Caesar (Panja) and mother of Kimba (Leo). Her story typically begins with capture by human poachers led by Viper Snakely (Hamegg). The hunters trap her using a recorded roar of Caesar, intending to use her as bait. This leads directly to Caesar's death. Their final moments differ: in the manga, they exchange no words before his slaughter, and Eliza independently names their unborn son Kimba. In the 1966 English dub and 1989 series, Caesar manages to request the name "Kimba" before dying.

Following Caesar's death, Eliza is transported via ship destined for a zoo. During the voyage, she gives birth to Kimba. About two months later, she urges Kimba to escape captivity, insisting he belongs in the jungle. She helps him slip through the cage bars. Shortly after his escape, a storm sinks the ship, resulting in her death. This sequence appears in the manga, the 1965 anime series, the 1966 English dub, and the 1989 remake.

After her death, Eliza reappears as a spiritual guide for Kimba. Her likeness manifests in the stars during his ocean struggle, offering encouragement. She also appears in flashbacks throughout later episodes and series, providing comfort, guidance, or singing to Kimba during moments of doubt or hardship, reinforcing her ongoing influence on his ideals and leadership.

The 2009 television special *Jungle Emperor: The Brave Can Change the Future* presents a different portrayal. Captured as a cub, Eliza is relocated to a human-created artificial "Neo-Jungle." In this adaptation, she survives the story's events and departs with other animals to seek a natural jungle at the conclusion. This is the only official adaptation where she does not die.

Her role remains consistent as a supportive mate to Caesar, often expressing concern for his safety during missions to free livestock from human villages. Her narrative function centers on catalyzing Kimba's journey and embodying themes of sacrifice and maternal resilience.