Sango Himeyuri is the older twin sister of Ruri Himeyuri, both serving as main heroines. She has light blue hair typically styled in twin buns and matching blue eyes. Her surname, Himeyuri, combines the characters for "princess" and "lily," while her given name Sango means "coral."

She exhibits a consistently bubbly, sweet, and emotionally open personality, forming a distinct contrast with her sister. Despite this outward demeanor, Sango demonstrates significant technical aptitude, having contributed to the development of next-generation maid gynoids for Kurusugawa Electronics. This proficiency coexists with a noted naivety and somewhat childish disposition. Within the twin dynamic, she frequently assumes an advisory role toward Ruri, positioning herself as the de facto older sister figure despite their shared age. Both sisters speak using a strong Kansai regional dialect.

Transported alongside others into a fantasy RPG world within the Dungeon Travelers narrative, Sango functions as a magic user within the player's party. The group navigates dungeons, battles monsters, and confronts challenges such as the abduction of Takaaki Kouno by Tamaki Kousaka, prompting their rescue efforts. Sango utilizes magical abilities in the party mechanics and becomes unlockable as a playable character after fulfilling specific in-game conditions.