Miki Saotome is one of the primary antagonists in the anime Moeyo Ken, serving as the cruel and ruthless leader of a villainous trio known as the Tsubame Group. She is a young woman with dark orange hair and orange eyes. Her background is rooted in the alternate Meiji era setting of the series, where supernatural entities must be registered with the government. Instead of complying with these laws, Miki Saotome and her group oppose the registration system and seek to return the local monsters to their untamed, original states. Her overarching motivations are to turn all monsters to her side, destroy both the city of Kyoto and the Mobile Shinsengumi, and eventually take over the world. This ambition drives her to repeatedly scheme against the protagonists, though her plans often follow a repetitive, comedic pattern similar to classic antagonist teams.

Within the story, Miki Saotome fulfills the role of the main recurring antagonist faction leader, persistently clashing with the Mobile Shinsengumi as they try to maintain peace and enforce the monster registration laws. Her key relationships are with her two subordinates, Ukon Tanaka and Sakon Suzuki, who accompany her in her schemes. The three function as a tight-knit unit, with Miki Saotome acting as the commanding force. There is little notable development for her character; she remains largely static throughout the narrative, consistently pursuing her world-domination goals without significant change in her personality or motivations. In terms of abilities, Miki Saotome is depicted as a capable leader and a skilled combatant, though the series does not detail any supernatural powers or specialized techniques. Her strength lies more in her determination and her ability to organize her group's operations against the Mobile Shinsengumi.