Akagi Honjō works as an operator at the Shinkansen Ultra Evolution Institute's Ōmiya Branch in Season 1, providing operational support against mysterious threats. By Season 2, he advances to acting director of the Kyoto Branch, a role entailing greater leadership responsibilities within the institute.

His professional connections include Ōmiya Branch colleagues Futaba Mihara, Daiya Oyama, and Minori Sanjo. During his time there, he reported to superiors Shinpei Izumi and Hokuto Hayasugi.

A personal interaction occurs in Episode 37, where he meets Futaba Mihara at Ueno's science museum. This encounter, casually framed as a pre-date meeting, highlights his human connections beyond duty, unfolding amidst discussions on human evolution during ongoing conflict.