Mikoto Ishino is the twin sister of Jin Ishino and a hero in the Mobile Rescue Police. She first appears in the third episode of the series. Her parents work overseas as doctors, a profession that inspires both siblings to pursue rescue work. Mikoto initially shares a Drive Head unit with her brother but later receives her own personal machine, Drive Head 03 Mk-II White Pearl Hope, during the web series.

Mikoto has an innocent and cheerful personality with a strong sense of femininity, often described as having high feminine energy. She is easygoing and follows her own pace, which makes her a relaxed presence within the team. Among the female students at her school, she is considered an idol because of her popularity and approachable demeanor. Like her twin brother, Mikoto possesses excellent calculation abilities, which prove useful in disaster scenes that require complex judgment and quick decision-making.

Her role in the story is that of a capable rescue driver who supports her teammates with both her analytical mind and her positive attitude. Her key relationship is with her brother Jin, with whom she shares a close bond and a complementary working style. Over the course of the series, she grows from sharing a robot to piloting her own Drive Head, demonstrating her increasing independence and competence as a rescuer. Her notable abilities include high-level computational skills that aid in tactical planning during emergencies, as well as her piloting talent that allows her to operate the White Pearl Hope effectively.