"Princess Resurrection" centers on Hiro Hiyorimi, a young man who becomes entangled in a supernatural conflict after encountering a mysterious and powerful girl named Hime. Hime, also known as the Princess of the Monster Realm, is a warrior princess tasked with battling monstrous entities that threaten both the human and monster worlds. Hiro, after being fatally injured, is revived by Hime using her blood, binding him to her service as a loyal servant and protector. This act grants him enhanced strength and resilience, making him a valuable ally in her ongoing battles.

The narrative unfolds as Hime and Hiro face a variety of supernatural threats, including vampires, werewolves, and other mythical creatures. Hime’s mission is to eliminate these monsters while maintaining a delicate balance between the human and monster realms. Her authority is frequently challenged by rival factions within the monster world, including her siblings, who seek to overthrow her and claim her throne. Each sibling possesses unique abilities and commands their own army of monsters, leading to intense and often violent confrontations.

Hime’s entourage grows as the story progresses, with additional characters joining her cause. Among them are Flandre, a vampire with a tragic past; Sawawa, a werewolf who initially opposes Hime but later becomes an ally; and Reiri, a cyborg assassin with a mysterious connection to Hiro. These characters contribute their unique skills and backgrounds to the group, creating a dynamic and diverse team.

The series blends action, horror, and dark fantasy, with a focus on the moral complexities of Hime’s mission. While she is determined to protect both worlds, her methods are often ruthless, raising questions about the cost of her actions. Hiro, as her human companion, serves as a moral counterpoint, frequently questioning the ethics of their battles and striving to find a more compassionate approach. This tension between duty and humanity forms a recurring theme throughout the story.

As the plot advances, deeper layers of the monster realm’s politics and history are revealed, including the origins of Hime’s family and the true nature of her powers. The series culminates in a climactic struggle for control of the monster realm, with Hime and her allies facing their greatest challenges yet. The resolution of these conflicts leaves lasting implications for both the human and monster worlds, while also exploring the evolving relationships between the characters.