The episode begins with Suika, after seven years of loneliness and tireless work, finally successfully reviving Senku with self-made revival fluid. Her relief and joy are overwhelming, and Senku honors her incredible achievement with the simple yet moving words: Well done, Suika. With Senku's help, the production of the fluid is drastically accelerated, and all the core members of the Kingdom of Science are gradually revived, culminating in a long-awaited and heartfelt reunion after all these years.

But the joy is short-lived, as the group must come to terms with a disturbing truth about the petrification devices, the Medusas. Tsukasa reveals that Hyoga was actually killed during the fight against Stanley. Since the recent global petrification nevertheless healed him, it is certain: The Medusa can not only heal injuries, but also bring the dead back to life. This discovery, which grants all of humanity potential immortality, immediately triggers a profound ethical debate. While Chrome is excited about the possibilities, Tsukasa and Dr. Xeno warn of the terrible consequences: An overpopulated, stagnant world where someone could absolutely control the power over life and death.

To protect this new, fragile world and finally solve the mystery of Why-Man, only one path remains: the journey to the moon. Senku revives Dr. Xeno and proposes an alliance to him. In exchange for Xeno's expertise in rocket science and his full cooperation, the Kingdom of Science will provide exonerating witness testimony for Stanley's actions. Xeno agrees to this elegant transaction, and the two brilliant scientists join forces to begin the seemingly impossible mission in the final cours: building a rocket in the Stone Age to reclaim the future of humanity.