George Takei has built a prolific career as a voice actor, bringing his distinctively rich and commanding tenor to a wide range of animated characters across film and television. While he is globally renowned for his live-action role as Hikaru Sulu in the Star Trek franchise, his voice work constitutes a significant and diverse body of his professional accomplishments. His entry into voice acting began in the 1950s, providing English dubbing for Japanese monster films such as Rodan and Godzilla Raids Again, an experience that initiated his long-standing connection to Japanese and anime-influenced storytelling.

His voice filmography includes prominent roles in major animated features. He voiced the First Ancestor in Disney's Mulan and its sequel Mulan II, a role that connects him to a film with significant cultural impact. He also contributed to the stop-motion film Kubo and the Two Strings, a project from Laika that shares thematic roots in Japanese culture and folklore. His other feature film credits include Free Birds, Paws of Fury: The Legend of Hank, and an extensive list of other animated projects.

In the realm of television animation, Takei has made numerous guest appearances, often lending his voice to characters that benefit from his authoritative yet expressive delivery. These roles span a wide variety of popular series. He voiced the Warden in the acclaimed series Avatar: The Last Airbender and was later cast as the voice of the ancient spirit Koh in its Netflix live adaptation. He played the villainous Ricardio in Adventure Time, and provided the voice of a Positive Reinforcement Machine in a single, memorable episode of Phineas and Ferb. He has also voiced characters in Kim Possible, The Simpsons, Futurama (frequently as the head of himself), Star Wars: The Clone Wars, and Amphibia, among many others.

His connection to anime and Japanese-influenced animation is particularly notable. In 2021, he joined the cast of Star Wars: Visions, an anthology series that reimagines the Star Wars galaxy through the lens of various Japanese anime studios. For the short film Akakiri, he provided the English voice for the character Senshuu, a travel guide who assists a princess and a Jedi Knight on their perilous journey. This role was not his first in the Star Wars animated universe, as he had previously voiced the Separatist General Lok Durd in Star Wars: The Clone Wars. His participation in Star Wars: Visions further cements his legacy as a bridge between Western science fiction and Japanese animation.

Throughout his voice acting career, Takei has demonstrated a recurring collaboration with major studios like Disney and a consistent presence in projects that celebrate or draw from Japanese culture. His instantly recognizable voice and his ability to imbue characters with humor, wisdom, or villainous depth have made his performances a highlight for audiences across generations. His work in animation stands alongside his extensive live-action career as a testament to his enduring talent and versatility as a performer.