Kether Donohue began her career as a voice actor at the age of thirteen, providing voices for English-language dubs of Japanese animated series and films. Her early work in anime includes roles in productions from the late 1990s and early 2000s, such as The King of Braves GaoGaiGar, Magical Doremi, and Piano: The Melody of a Young Girl's Heart. Throughout the 2000s, she built an extensive filmography of voice roles in anime. She is known for voicing Skuld in Ah! My Goddess, Midori Kasugano in Midori Days, and Kiki Benjamin in Mew Mew Power. From 2006 to 2008, she voiced the character Lily in the original animated series Kappa Mikey, which blends anime and western animation styles. One of her notable roles from this period is Zoe Drake in the series Dinosaur King, where she voiced the main heroine of the D-Team. Her other prominent anime credits include voicing Makiko in Let's Go! Tamagotchi, various characters in the Pokémon anime including Candice and Autumn, and Angela Rains in Yu-Gi-Oh! 5D's. Information about recurring collaborations with specific directors or other voice actors is not documented in available sources. While Donohue has had a prolific career in voice acting, no specific awards for her anime voice work are mentioned in the available information.