Ayumi Sena is a Japanese voice actress born on September 30, 1975, in Chiba Prefecture, Japan. She is affiliated with the talent agency Yu-rin Pro. Her journey into voice acting began when she enrolled in a voice acting school run by fellow voice actress Keiko Yokozawa, who also gave her the stage name "Ayumi Sena". Earlier in her career, she also performed under the stage name Tomoe Sakuragawa.

Sena's career, which started in the early 2000s, is marked by a wide variety of roles in anime, video games, and dubbing for foreign films. She is perhaps best known for her long-running role as Yuzu Kurosaki, the younger sister of the protagonist, in the popular anime series Bleach, a character she voiced for nearly two decades across the television series, multiple OVAs, and theatrical films such as Bleach: Memories of Nobody and Bleach: The DiamondDust Rebellion. In the same series, she also voiced the characters Ayame and the Arrancar Cyan Sung-Sun. Another significant and recurring role is Honoka Shirahama in Kenichi: The Mightiest Disciple.

Beyond these prominent parts, Sena has built a career as a versatile character actor in long-running family anime. Her extensive filmography includes guest and supporting roles in Doraemon, Crayon Shin-chan, Atashin'chi, Nintama Rantaro, Case Closed, and Soreike! Anpanman. She also provided the voice for the character Ukkari in the series Denkō Chō Tokkyū Hikarian - Lightning Attack Express, as noted in her agency profile and other reliable databases.

In addition to anime, Sena's work extends to video games, including roles in the Tales of series such as Tales of the Tempest and Tales of Phantasia, as well as The Oneechanbara series. She is also active in narration for television programs and promotional videos, drama CDs, and audio books. Her known hobbies include cooking and knitting.