Dameon Clarke is a Canadian actor known for his extensive work in anime voice acting, video games, and live-action television and film. Born in Mississauga, Ontario, he began his acting career at the age of eleven. He is closely associated with Funimation Productions, where he has lent his voice to numerous prominent characters in English dubs of popular anime series.

In anime, Clarke is perhaps best recognized for portraying iconic antagonists and powerful figures. His roles include the villainous Cell in the Dragon Ball series, including Dragon Ball Z and Dragon Ball Super. He also voiced the formidable Younger Toguro in Yu Yu Hakusho and the vengeful Scar in Fullmetal Alchemist. Further demonstrating his range, he played Proxy One in Ergo Proxy and Victor Hilshire in Gunslinger Girl. Notably, he has voiced the character Kazuma Soma in both the 2001 adaptation of Fruits Basket and its 2019 reboot, Fruits Basket the Final, reprising the role nearly two decades later. His other anime credits include George Kaminski in Case Closed and roles in Blue Gender and Kiddy Grade.

Beyond anime, Clarke has achieved significant acclaim in the video game industry. He is the voice of the charismatic and manipulative villain Handsome Jack in the Borderlands series, a role he has played in Borderlands 2, Borderlands: The Pre-Sequel!, and Tales from the Borderlands. He has also provided voices for other major game franchises, such as Nathan Spencer in Marvel vs. Capcom 3, Rolento in Street Fighter X Tekken, and Arngrim in Valkyrie Profile 2: Silmeria. Clarke's performance as Handsome Jack earned him the Spike Video Game Award for Best Performance by a Human Male in 2012.

In addition to his voice work, Clarke maintains an active on-camera career. He has appeared in recurring and guest-starring roles in numerous television series, including Graceland, How to Get Away with Murder, 24, Castle, Supernatural, and Prison Break. He is noted for having guest-starred on all three series in the CSI franchise and two in the NCIS franchise. His film work includes roles in A Scanner Darkly and I Love You Phillip Morris. He also starred in the independent film How to Be a Serial Killer, for which he won Best Actor awards at both the New York City Horror Film Festival and Shriekfest.