Ryan Wickerham is an American actor with a career spanning live-action film, television, and voice acting for animation and video games. His entry into performance began in his teenage years in Austin, Texas, where he was hired to work on a radio morning show after making impressions during a call-in segment. This opportunity led him to pursue stand-up comedy and secure an agent, which subsequently opened doors to voice-over and film acting work.

Wickerham has contributed voices to the English-language adaptations of several anime series. His credits in this field include the role of Iron Caesar in the original video animation (OAV) Shuten Doji. His other anime voice work encompasses a range of characters, such as Kichihoshi in Black Lion, Beast and Yuichi Kitano in Devil Lady, various characters in Jing: King of Bandits, multiple roles including Howard, Justice, and the Steam King in Steam Detectives, Pajama in Wedding Peach, and Sean Barrett in Zone of the Enders.

Beyond anime, a significant portion of Wickerham's voice acting career has been in the video game industry. He has voiced characters for major companies like Microsoft Game Studios, Warner Bros. Interactive Entertainment, and Sony Online Entertainment. A prominent and recurring role is in the long-running game DC Universe Online, where he provides the voices for iconic characters such as the original Flash (Jay Garrick), Captain Cold, and Metallo. He has also described his early experience voicing the characters Steve and the Sergeant at Arms in the cult classic video game Harvester as a formative trial that prepared him for future work in cartoons and games. In addition to his performance work, Wickerham has also worked as a writer and producer on independent film projects.