Jim Belushi provided the English voice for the character Takashi in the Studio Ghibli animated film My Neighbors the Yamadas. Released in 1999, this film marks his sole, widely recognized credit in the realm of anime voice acting. In the English-language adaptation produced for the film's release in the United States, Belushi was cast in the role of the father, Takashi Yamada, bringing his distinct vocal style to the character.

Belushi's involvement in My Neighbors the Yamadas represents a specific instance of an American actor being recruited for a localized version of a major Japanese animation title. His casting was part of a dubbed track that featured other notable North American performers, intended to make the film more accessible to English-speaking audiences. While the film itself is a celebrated work from director Isao Takahata, known for its episodic storytelling and unique visual style, Belushi's contribution is specifically tied to this English-dubbed version.

Beyond this particular role, Belushi has had an extensive and varied career as a voice actor in animation, though his work has been primarily in American-produced series and films. His voice acting career began in the 1990s with a recurring role as Simon the Monster Hunter in the Nickelodeon series Aaahh!!! Real Monsters. He went on to provide voices for numerous other animated projects, including characters in The Mighty Ducks, Gargoyles, Hey Arnold!, and the Disney film The Wild. However, these credits are for English-language animation and do not constitute further work in Japanese anime, distinguishing his role in My Neighbors the Yamadas as his primary foray into that specific field.