Kazuhiko Tsuzuki is a Japanese manga artist and illustrator, born on May 19, 1962. He began his professional career as a manga artist after graduating from school, making his debut in 1982 with the work Shishigami Sango. Early in his career, he was employed by the video game company Nihon Falcom, where he worked as an in-house artist. During his tenure at Falcom in the late 1980s, he contributed graphic and character design to several prominent games, including Ys II and the original Ys. He also created a manga adaptation of the Falcom game Xanadu in 1987, developing an original story that blended fantasy and science fiction elements.

Tsuzuki is best known as the illustrator for the light novel series The Most Irresponsible Man in Space, written by Hitoshi Yoshioka. The first volume of this series was published by Fujimi Shobo on January 25, 1989. The series was later adapted into the popular anime The Irresponsible Captain Tylor, which first aired as a television series in 1993. For the anime adaptation, Tsuzuki is credited for the original character designs and illustrations. His visual designs were also used for the subsequent original video animation sequel released between 1994 and 1996. The light novel series proved to be long-running, with numerous sequel series and spin-offs published over the following decades, including a special deluxe edition in 2012 that again featured Tsuzuki's illustrations.

Prior to his work on The Irresponsible Captain Tylor, Tsuzuki was the original creator of the manga Izumo, which was later adapted into a two-episode original video animation in 1991. He is also credited as the author of the manga SS Digger in 1993 and Planet Brute in 1990. His artistic identity is marked by a blend of fantasy and science fiction concepts, as seen in his early work on Xanadu. A personal message from the author, which appears in his published works, states, You must not forget love, justice, and courage. Tsuzuki has also worked on character design for the video game Hip no Ue no Dōkyonin in 1998.