Rio Akisaki is a Japanese manga artist and illustrator. Information indicates Akisaki is female and from Gifu Prefecture, Japan. She is active as a creator of doujinshi through her circle, Rio Labo. Akisaki has established her professional career by working on several manga series, both as an artist for adaptations of light novels and as an original creator.

One of Rio Akisaki's most significant credits is as the artist for the manga adaptation of the light novel series I'm a Noble on the Brink of Ruin, So I Might as Well Try Mastering Magic. The original story is written by Nazuna Miki. Akisaki began serializing the manga adaptation in February 2020 on the Comic Corona web manga service, which is operated by TO Books. The series was later collected into multiple tankōbon volumes and has been published in English by J-Novel Club. The success of the franchise, including Akisaki's manga adaptation, led to the production of an anime television series that aired from January to March 2025.

Beyond this high-profile adaptation, Akisaki has contributed to other manga series. She provided the art for VRMMO de Summoner Hajimemashita, which was published from January 2018 to November 2019. She is also the author and artist for the original manga Fuuin Maou wa Mederaretai, which was serialized from August 2019 to 2022. Additional illustration work includes providing art for the light novel Akuyaku Reijou ni Nanka Narimasen. I'm a Noble on the Brink of Ruin, So I Might as Well Try Mastering Magic remains her most prominent work to date, and she continues to be active in the industry as a professional manga artist.