Keisuke Makino is a Japanese freelance screenwriter, novelist, and creator of manga and anime works, born in 1980 in Okazaki City, Aichi Prefecture. He currently lives in Tokyo and is a member of the Writers Guild of Japan. Makino graduated from Doshisha University's Faculty of Letters, where he majored in Aesthetics and Art Studies. His professional writing career began with accolades in screenwriting, including being a finalist for the 32nd Kido Award in 2006, winning an award at the 9th Japan Film Angel Grand Prix in 2007, and being selected for the 1st TBS Drama Script Grand Prix in 2008. His work in film has also been recognized internationally; the movie Abductee, for which he wrote the script, won the Grand Prize at the 14th Buenos Aires Rojo Sangre Film Festival in 2013.

Makino is best known as the original creator of the science fantasy light novel series Tsuki to Laika to Nosferatu, also known as Irina: The Vampire Cosmonaut. The series was published by Shogakukan under their Gagaga Bunko imprint, with illustrations by Karei. Seven volumes were released between December 2016 and October 2021. The series has been commercially and critically successful, ranking fourth in the bunkobon category and third among new works in Kono Light Novel ga Sugoi! 2018 guidebook. In 2022, the Tsuki to Laika to Nosferatu series won the Seiun Award in the Best Japanese Long Story category.

The success of the light novel led to multiple adaptations. A manga adaptation, with Makino serving as the original story writer and art provided by Sojihogu, began serialization in Kodansha's Comic Days digital magazine in March 2018 and concluded in March 2023, collected into two volumes. An anime television series adaptation produced by Arvo Animation aired from October to December 2021. For the anime, Makino was responsible for the series composition and wrote the scripts for several episodes, including the first, second, sixth, seventh, and twelfth. The story is set in an alternate post-World War II era where two superpowers are locked in a space race. It follows Lev Leps, a young cosmonaut candidate, who is assigned to train Irina Luminesk, a vampire girl used as a test subject for the secret Nosferatu Project. The narrative explores themes of prejudice, ambition, and the personal bonds formed between the two protagonists as they share the dream of traveling to the moon.

Beyond this flagship series, Makino has worked across various media. His other literary works include the novel series Flick & Break published by Shogakukan, Abducti Tekishaseizon, and a short story contribution to the Sword Art Online IF Official Novel Anthology. As a manga original creator, he also provided the story for Kōya ni Kemuru wa Shi no Kaori, illustrated by Zakiko and serialized in Monthly Comic Zero Sum. In live-action film and television, Makino's screenwriting credits include HiGH&LOW THE RED RAIN, Oh My God!, and an adaptation of Sayonara Debussy. He has also written scripts for television dramas such as Rookie and Shima Shima.

Makino has also been involved in music and stage production, having released a demo CD in Iceland in 2008 and a first album under the name bio tolva in 2012. He has also served as the original author, scriptwriter, and director for the stage play segment of a live concert event based on his Tsuki to Laika to Nosferatu series. His professional website notes that due to a busy schedule, he is not currently accepting new project proposals. Makino's career demonstrates a versatility across novels, manga, anime, and live-action film, though he remains most significantly recognized for creating the Tsuki to Laika to Nosferatu franchise.