Jun Mayuzuki is a Japanese manga artist born on April 27, 1983, in Yokohama, Kanagawa Prefecture. Growing up in a household where both parents loved manga, she was surrounded by the medium from an early age and particularly enjoyed reading shoujo magazines such as Ribon and Nakayoshi. Mayuzuki made her professional debut in 2007 or 2008 with the short story Farewell, Daisy, which won the bronze prize in Shueishas first Gold Pine Cone Award. She initially published several one-shots in shoujo magazines but found the genres conventions including idealized romantic elements to be restrictive. Seeking greater creative freedom, she submitted her work to various publishers across different demographics before finding her place in seinen magazines, where she felt the anything goes approach better suited her style.

Her first serialized work was Iromon, published in Shogakuhans Monthly Big Comic Spirits from 2013 to 2014. She achieved widespread recognition with her second serialization, After the Rain, which ran from 2014 to 2018. The story follows a high school girl who works at a family restaurant and harbors feelings for the middle-aged manager. The manga received the 63rd Shogakukan Manga Award in the general category in 2018 and was adapted into both an anime television series produced by Wit Studio in 2018 and a live-action film the same year. Mayuzuki has described After the Rain as representing her past self and the emotions she was processing at that time.

In November 2019, Mayuzuki launched Kowloon Generic Romance in Shueishas Weekly Young Jump. The series is set in a reimagined Kowloon Walled City, the famously dense and now-demolished enclave in Hong Kong. She has stated that her fascination with Kowloon began in elementary school after watching a television documentary, and she held a long-standing desire to create a manga set there but could not find the right story until after finishing After the Rain. The manga blends office romance with mystery and science fiction elements, exploring themes of memory, identity, and nostalgia. As of 2025, the series remains in publication with multiple collected volumes. An anime television adaptation produced by Arvo Animation premiered in April 2025, and a live-action film is scheduled for release in August 2025. Mayuzuki has noted that while After the Rain reflected her past, Kowloon Generic Romance represents her present thoughts and feelings, with nostalgia being a theme she wishes to explore indefinitely.

Mayuzukis short story collection Farewell, Daisy, published in English in 2025, compiles works from 2007 to 2017 and demonstrates her range as a storyteller. The collection includes stories that frankly address sexuality, identity, and womens experiences from a female perspective, featuring characters such as a feminist author with a complicated relationship to intimacy, a young woman struggling with an eating disorder, and a trans womans search for connection. These early works reveal her willingness to confront unconventional and adult subject matter.

Regarding her artistic approach, Mayuzuki has described being highly conscious of rhythm and tempo when constructing her storyboards, likening her process to a composer writing music. She cites Neon Genesis Evangelion as an influence on her sense of narrative rhythm. While she has incorporated some digital tools for touch-ups, she primarily draws by hand, including all covers for Kowloon Generic Romance. She works with assistants who help realize the intricate, detailed backgrounds that characterize her recent art.

Mayuzuki has shared that her characters often draw from real life. Her editor noted that the protagonist Reiko Kujirai from Kowloon Generic Romance shares her personality, and the character Hajime Kudou was modeled after a former editor who helped connect her with her current editorial team. She has cited Ai Yazawas Tenshi Nanka ja Nai as the first manga she followed from beginning to end. Her advice to aspiring creators is to not compromise on what they love.