Saki Ono is a Japanese voice actress born in Tokyo on November 26, 1990. She began her career in the entertainment industry in 2012 with a theater company and made her debut as a voice actress in 2013. Her first starring role in a television anime came in 2015, when she was cast as the titular character Hakone-chan in the series Onsen Yōsei Hakone-chan.

Ono is perhaps best known for her work within the Kemono Friends franchise. She voiced the character Common Raccoon in the original 2017 television anime Kemono Friends, a role she reprised for the 2019 sequel Kemono Friends 2, in which she also voiced the character Giant Pangolin. Her involvement with the franchise extended beyond voice acting; she became a member of the voice actor unit Doubutsu Biscuits, formed with her co-stars Yuka Ozaki and Kana Motomiya. As part of this unit, she performed the opening theme song for the first anime series, Yōkoso Japari Park e. The unit Doubutsu Biscuits, along with the group PPP, was recognized for their musical contributions to the franchise, winning a singing award at the 12th Seiyu Awards. Ono also appeared in the stage adaptation of Kemono Friends in 2017, again playing the role of Common Raccoon.

In addition to her prominent roles in the Kemono Friends series, Ono has taken on a variety of other characters. In 2018, she played the role of Yuka Endo in the anime series Beatless and Beatless Final Stage. Her other notable anime credits include Aiko Nishikawa in Nazotokine (2016), Romi Oze in Venus Project -Climax- (2015), and Nyaossyi in Funassyi no Funafunafuna Biyori (2015). She has also lent her voice to numerous video game characters, such as Mikuni Haruyama in Massage Freaks (2022), Mikoto Barcher in Genkai Totsu-jō: Castle Panzers (2017), and Claris Rigby in Company Girls (2016).

Throughout her career, Ono has been affiliated with several talent agencies. She was previously represented by Seinenza Theater Company Movie Broadcast and later by Just Production, before announcing her departure from Just Production in April 2019. In September 2020, she joined the agency Office Anemone.