Rina Misaki is a Japanese voice actor known professionally for her work in adult-oriented anime and video games. The name Rina Misaki is a stage alias used by the established voice actor Shizuka Ito for performances in roles intended for mature audiences. This practice of using a pseudonym is common among voice actors in the industry to separate their mainstream work from roles in adult content. Her associated names in such credits include the kanji variations 美咲 里奈 and 三咲 里奈.

Her career in this area is extensive, with a significant number of credits in adult video games, particularly during the 2000s and 2010s. Prominent game roles performed under the name Rina Misaki include Takasaki Mayuki in the Da Capo II series, Mifuyu Kisaragi in Tayutama: Kiss on my Deity, and Christiane Friedrich in the Maji de Watashi ni Koi Shinasai! series. Another frequently cited role is Saya Kamijo from Happiness!. Her work in this medium has also included performances on character song CDs related to these games.

In anime, a key recent role credited to Rina Misaki is Kaede Shiina in the 2024 short-form anime series Adam's Sweet Agony. In this series, she voices a teacher character, described as one of the key female figures pursuing the protagonist. Her performance is part of the original Japanese cast for the show, which is produced under the AnimeFesta brand. This role is a primary example of her on-screen anime voice work using this specific alias.