Ann Dowd is an American actress whose extensive career in film and television led to her entry into anime voice acting with the 2024 Netflix series Terminator Zero. While she is widely recognized for her live-action performances, particularly her Emmy Award-winning role as Aunt Lydia in The Handmaid's Tale, her work in Terminator Zero represents a significant foray into the animation medium.

In Terminator Zero, an anime series set within the Terminator franchise, Dowd provides the voice for a character known as the Prophet. Set in a post-apocalyptic future, the Prophet is described as a philosophical guide and a source of hope for the human resistance, leading survivors through the darkness of a world dominated by machines. The series, which premiered on August 29, 2024, was produced by the renowned Japanese animation studio Production I.G and features a voice cast that also includes Timothy Olyphant, Rosario Dawson, and André Holland.

Prior to Terminator Zero, Dowd's voice acting credits were limited, with previous work including the 2009 film The Toe Tactic and the first season of the animated series The Third Wheel: The Tales of Three-Finger in 2018. Her casting in a major anime production like Terminator Zero brought her acclaimed dramatic skills to the genre. There are no documented recurring collaborations with specific anime directors or studios beyond this single, prominent project. Her career remains primarily defined by her extensive and award-nominated work in live-action film and television.