Sky Santacruz is a Mexican American voice actress based in Los Angeles, California. She began her voice acting journey in March 2021, initially auditioning for singing projects on the casting platform Casting Call Club before moving into voice over for anime and animation. Before pursuing voice acting professionally, Santacruz experienced stage fright and secretly recorded impressions of cartoon characters on her iPod. She cites voice actors Laura Bailey and Ashley Johnson as inspirations for her approach to character work.

Santacruz provides the English voice for the character Suzu in the series Hotori: Simply Wishing for Hope. She also voices the character Kokuto in the English dub of the series SHIBOYUGI: Playing Death Games to Put Food on the Table. In addition to these roles, she performed as an extra in the animated film The World’s Divide, voicing the character Valkyrie Command.